Q: My child got a Peramivir IV for the flu but no oral flu meds. Do we need a new prescription?
- Myeongchan Kim
- Jun 12
- 2 min read
Medically reviewed by Sang Hyun Ahn, MD
Content edited by Myeongchan Kim, MD
This post is a dramatization of a question and answer session experienced by our actual medical reviewers. Please note that this content is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

Question:
Two days ago, my child was diagnosed with the flu and received a Comifluence (Peramivir) IV injection. However, I noticed that there is no antiviral flu medication included in the oral prescription we were given. Is it okay for my child not to take an oral flu medicine, or should I go back to the hospital to get a prescription for it?
Answer:
I understand your concern about not finding an oral flu medication in your child's prescription after they received the IV treatment.
Comifluence (Peramivir) is an intravenous antiviral medication for the flu, and a single dose is considered a complete treatment. It provides the exact same therapeutic effect as taking an oral medication like Tamiflu for five days. Therefore, if your child received this IV treatment, they do not need to take any additional oral antiviral flu medications.
It is perfectly normal that the oral prescription you received only includes symptom-relief medications, such as fever reducers or cough suppressants.
Things to monitor after the IV treatment:
• Symptom Improvement: Check whether the fever, cough, and body aches are gradually subsiding.
• Timing: The IV treatment is most effective when administered within 48 hours of symptom onset.
• Current Medications: Taking just the prescribed symptom-relief medications is the correct and expected approach.
For now, simply administer the prescribed symptom relievers, ensure your child gets plenty of rest, and encourage sufficient fluid intake.
When to revisit the hospital:
Please seek an in-person medical evaluation if you notice any of the following warning signs:
• The fever persists or worsens after 3 days.
• Your child experiences difficulty breathing or chest pain.
• Symptoms temporarily improve but then suddenly worsen again.

For extra peace of mind and clear guidance when tracking your child's symptoms, the FeverCoach app is always there to help.




