Q: Low-grade fever returned after finishing treatment for macrolide-resistant Mycoplasma pneumonia. Should I see a doctor again?
- Myeongchan Kim
- May 29
- 3 min read
Medically reviewed by Sang Hyun Ahn, MD
Content edited by Myeongchan Kim, MD
This post is a dramatization of a question and answer session experienced by our actual medical reviewers. Please note that this content is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.

Question:
My child recently went through a long treatment for pneumonia. It started with a high fever (39°C) and a severe cough. Flu tests were negative. After trying a few different antibiotics (amoxicillin, azithromycin, and cefditoren) along with steroids, the fever finally started to drop. A test later confirmed a macrolide-resistant Mycoplasma infection, so we completed a full 10-day course of doxycycline.
By the end of the treatment, the temperature was in the low 37°C range, and the doctor concluded our visits. However, since stopping the medication, a low-grade fever has slowly returned, fluctuating between 37.7°C and 37.9°C. There are no other symptoms. I tried giving fever reducers, but the temperature only drops to about 37.3°C. Interestingly, during sleep, the body temperature returns to a normal 36.6°C without any medication. Should we go back to the clinic for a follow-up?
Answer:
It is completely understandable to be concerned about a lingering low-grade fever after treating Mycoplasma pneumonia, especially after such a long and complex treatment process. You have done a great job managing this so far.
Current Assessment:
A temperature of 37.7°C to 37.9°C falls into the low-grade fever range.
Having a normal body temperature during sleep (36.6°C) is a very positive sign.
The absence of other respiratory symptoms is also highly encouraging.
Reasons for the Lingering Low-Grade Fever:
Lung Recovery Process: It typically takes 2 to 4 weeks for lung tissue to completely heal and recover after a pneumonia infection.
Ongoing Immune Response: The body may still be in the process of clearing out residual inflammation.
Temperature Sensitivity During Activity: During the recovery phase, the body's temperature regulation system can become more sensitive, causing slight elevations in temperature during normal daytime activities (which explains why the temperature is completely normal during restful sleep).
Since the 10-day course of doxycycline was completed and the sleeping temperature is normal, there does not appear to be a need for an urgent clinic visit right now.
What You Can Do Now:
Ensure plenty of rest and adequate fluid intake.
Avoid strenuous physical activities until the body is fully recovered.
Keep a log of the body temperature at different times of the day.
Only use fever reducers if the low-grade fever is causing visible discomfort.
When to Revisit the Doctor:
You should bring your child in for an in-person medical evaluation if any of the following occur:
The fever spikes to 38°C or higher.
Respiratory symptoms (such as cough, phlegm, or shortness of breath) return.
There is a noticeable decrease in appetite or overall energy levels.
The low-grade fever persists for more than one week.
If this low-grade fever continues in the exact same pattern after a week, please consult your pediatrician. A follow-up chest X-ray may be necessary to accurately verify the healing progress of the lungs.

For extra peace of mind and clear guidance when tracking your child's symptoms, the FeverCoach app is always there to help.




