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Q: My 27kg child has a fever over 39°C after taking Ibuprofen for the flu. Can I give Acetaminophen now?

Medically reviewed by Sang Hyun Ahn, MD

Content edited by Myeongchan Kim, MD


This post is a dramatization of a question and answer session experienced by our actual medical reviewers. Please note that this content is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional for any health concerns or before making any decisions related to your health or treatment.


Illustration for the question: My 27kg child has a fever over 39°C after taking Ibuprofen for the flu. Can I give Acetaminop…

Question:

My 27kg (about 60 lbs) child was diagnosed with the flu. They had a mild fever and a sore throat, so I gave them 5 mL of Ibuprofen an hour ago. However, their fever has now spiked to over 39°C (102.2°F). Can I give Acetaminophen right now to help bring the fever down?


Answer:

It is completely understandable to be worried when your child's fever spikes despite having taken medication after a flu diagnosis.


【What You Can Do Now】

• Since you gave Ibuprofen just one hour ago, you should wait until at least 2 hours have passed before giving Acetaminophen.

• Acetaminophen dosage for a 27 kg child: The recommended dose is 270–405 mg.

  • If your Acetaminophen liquid is labeled "160 mg/5 mL", you can give 8.5–12.5 mL (about 10 mL is a good standard dose).

  • Always use the provided dosing syringe or cup for an accurate measurement.

• Dress your child in light, breathable clothing, keep the room temperature comfortable, and encourage frequent, small sips of fluids to prevent dehydration.


【Medication Spacing and Intervals】

• Alternating medications: Leave at least a 2 to 3-hour gap between giving Ibuprofen and Acetaminophen.

• Acetaminophen: Can be given every 4–6 hours, up to a maximum of 5 times per 24-hour period.

• Ibuprofen: Can be given every 6–8 hours, up to a maximum of 4 times per 24-hour period.

• Always strictly observe the individual interval limits for each medication type.


【When to Seek Immediate Medical Care】

Please visit an urgent care clinic or the ER today if you observe any of the following warning signs:

• Breathing difficulties or chest retractions (the skin pulling in under the ribs when breathing).

• No urination for more than 8 hours.

• Extreme lethargy, constantly lying down, inability to stay awake, or poor eye contact.

• A fever that worsens or persists for more than 48 hours despite using fever-reducing medications.


Fevers caused by the flu can typically fluctuate for 3 to 5 days. If your child is drinking water, urinating, and responding well when awake, you can continue to monitor them safely at home. However, if any of the warning signs mentioned above appear, please have your child evaluated by a doctor immediately.

Illustration for a doctor's answer about: My 27kg child has a fever over 39°C after taking Ibuprofen for the flu. Can I give…

For extra peace of mind and clear guidance when tracking your child's symptoms, the FeverCoach app is always there to help.







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